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Forces on Nascent Polypeptides during Membrane Insertion and Translocation via the Sec Translocon

During ribosomal translation, nascent polypeptide chains (NCs) undergo a variety of physical processes that determine their fate in the cell. This study utilizes a combination of arrest peptide experiments and coarse-grained molecular dynamics to measure and elucidate the molecular origins of forces...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Niesen, Michiel J.M., Müller-Lucks, Annika, Hedman, Rickard, von Heijne, Gunnar, Miller, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303271/
https://ncbi.nlm.nih.gov/pubmed/30366631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.10.002
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