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A bi-phasic pulling force acts on transmembrane helices during translocon-mediated membrane integration

Membrane proteins destined for insertion into the inner membrane of bacteria or the endoplasmic reticulum membrane in eukaryotic cells are synthesized by ribosomes bound to the bacterial SecYEG or the homologous eukaryotic Sec61 translocon. During co-translational membrane integration, transmembrane...

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Hlavní autoři: Ismail, Nurzian, Hedman, Rickard, Schiller, Nina, von Heijne, Gunnar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553220/
https://ncbi.nlm.nih.gov/pubmed/23001004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2376
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