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A bi-phasic pulling force acts on transmembrane helices during translocon-mediated membrane integration
Membrane proteins destined for insertion into the inner membrane of bacteria or the endoplasmic reticulum membrane in eukaryotic cells are synthesized by ribosomes bound to the bacterial SecYEG or the homologous eukaryotic Sec61 translocon. During co-translational membrane integration, transmembrane...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553220/ https://ncbi.nlm.nih.gov/pubmed/23001004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2376 |
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