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Hydrophobic Blocks Facilitate Lipid Compatibility and Translocon Recognition of Transmembrane Protein Sequences

[Image: see text] Biophysical hydrophobicity scales suggest that partitioning of a protein segment from an aqueous phase into a membrane is governed by its perceived segmental hydrophobicity but do not establish specifically (i) how the segment is identified in vivo for translocon-mediated insertion...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Stone, Tracy A., Schiller, Nina, von Heijne, Gunnar, Deber, Charles M.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2015
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341838/
https://ncbi.nlm.nih.gov/pubmed/25635746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5014886
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