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Charge-driven dynamics of nascent chain movement through the SecYEG translocon

On average, every fifth residue in secretory proteins carries either a positive or a negative charge. In a bacterium such as Escherichia coli, charged residues are exposed to an electric field as they transit through the inner membrane, which should generate a fluctuating electric force on a translo...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Ismail, Nurzian, Hedman, Rickard, Lindén, Martin, von Heijne, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338579/
https://ncbi.nlm.nih.gov/pubmed/25558985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2940
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