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Competitive Binding of the SecA ATPase and Ribosomes to the SecYEG Translocon

During co-translational membrane insertion of membrane proteins with large periplasmic domains, the bacterial SecYEG complex needs to interact both with the ribosome and the SecA ATPase. Although the binding sites for SecA and the ribosome overlap, it has been suggested that these ligands can intera...

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Autors principals: Wu, Zht Cheng, de Keyzer, Jeanine, Kedrov, Alexej, Driessen, Arnold J. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318685/
https://ncbi.nlm.nih.gov/pubmed/22267723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297911
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