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Cotranslational folding of membrane proteins probed by arrest-peptide–mediated force measurements

Polytopic membrane proteins are inserted cotranslationally into target membranes by ribosome–translocon complexes. It is, however, unclear when during the insertion process specific interactions between the transmembrane helices start to form. Here, we use a recently developed in vivo technique to m...

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Détails bibliographiques
Auteurs principaux: Cymer, Florian, von Heijne, Gunnar
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767533/
https://ncbi.nlm.nih.gov/pubmed/23959879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306787110
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