Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion

BACKGROUND: During ageing an altered redox balance has been observed in both intracellular and extracellular compartments, primarily due to glutathione depletion and metabolic stress. Maintaining redox homeostasis is important for controlling proliferation and apoptosis in response to specific stimu...

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Detalhes bibliográficos
Main Authors: Carilho Torrao, Rita Barreto Duarte, Dias, Irundika HK, Bennett, Stuart J, Dunston, Christopher R, Griffiths, Helen R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766689/
https://ncbi.nlm.nih.gov/pubmed/24007191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-150
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