Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Elevated total cholesterol in midlife has been associated with increased risk of dementia in later life. We have previously shown that low-density lipoprotein (LDL) is more oxidized in the plasma of dementia patients, although total cholesterol levels are not different from those of age-matched cont...

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Hlavní autoři: Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C., Lip, Gregory Y.H., Griffiths, Helen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2014
Témata:
Original Contribution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180009/
https://ncbi.nlm.nih.gov/pubmed/25048970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.07.012
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