Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia

Oxysterols (OHC) are biologically active cholesterol metabolites circulating in plasma that may be formed enzymatically (e.g. 24S-OHC, 25-OHC and 27-OHC) or by autoxidative mechanisms (e.g. 7-ketocholesterol, 7β-OHC and 25-OHC). Oxysterols are more soluble than cholesterol and are reported to exert...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Dias, Irundika H.K., Milic, Ivana, Lip, Gregory Y.H., Devitt, Andrew, Polidori, M. Cristina, Griffiths, Helen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952874/
https://ncbi.nlm.nih.gov/pubmed/29501047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.02.014
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