Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion

BACKGROUND: During ageing an altered redox balance has been observed in both intracellular and extracellular compartments, primarily due to glutathione depletion and metabolic stress. Maintaining redox homeostasis is important for controlling proliferation and apoptosis in response to specific stimu...

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Hauptverfasser: Carilho Torrao, Rita Barreto Duarte, Dias, Irundika HK, Bennett, Stuart J, Dunston, Christopher R, Griffiths, Helen R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766689/
https://ncbi.nlm.nih.gov/pubmed/24007191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-150
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