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Glutathione Depletion and Disruption of Intracellular Ionic Homeostasis Regulate Lymphoid Cell Apoptosis

Intracellular glutathione (GSH) depletion is an important hallmark of apoptosis. We have recently shown that GSH depletion by its extrusion regulates apoptosis independently of excessive reactive oxygen species accumulation. However, the mechanisms by which GSH depletion regulates apoptosis are stil...

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Detalhes bibliográficos
Main Authors: Franco, Rodrigo, DeHaven, Wayne I., Sifre, Maria I., Bortner, Carl D., Cidlowski, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605975/
https://ncbi.nlm.nih.gov/pubmed/18940791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807061200
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