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Distinct FAK activities determine progenitor and mammary stem cell characteristics

Mammary stem (MaSCs) and progenitor cells are important for mammary gland development and maintenance and may give rise to mammary cancer stem cells (MaCSCs). Yet there remains limited understanding of how these cells contribute to tumorigenesis. Here we show that conditional deletion of focal adhes...

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Hlavní autoři: Luo, Ming, Zhao, Xiaofeng, Chen, Song, Liu, Suling, Wicha, Max S., Guan, Jun-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766468/
https://ncbi.nlm.nih.gov/pubmed/23832665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1351
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