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Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer

Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase identified as a key mediator of intracellular signaling by integrins, a major family of cell surface receptors for extracellular matrix, in the regulation of different cellular functions in a variety of cells. Upon activation by integrins...

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Detalhes bibliográficos
Autor principal: Guan, Jun-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848709/
https://ncbi.nlm.nih.gov/pubmed/20101634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.303
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