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Distinct FAK activities determine progenitor and mammary stem cell characteristics

Mammary stem (MaSCs) and progenitor cells are important for mammary gland development and maintenance and may give rise to mammary cancer stem cells (MaCSCs). Yet there remains limited understanding of how these cells contribute to tumorigenesis. Here we show that conditional deletion of focal adhes...

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Detalhes bibliográficos
Main Authors: Luo, Ming, Zhao, Xiaofeng, Chen, Song, Liu, Suling, Wicha, Max S., Guan, Jun-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766468/
https://ncbi.nlm.nih.gov/pubmed/23832665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1351
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