BRCA1 regulates human mammary stem/progenitor cell fate

Although it is well established that women with germ-line mutations in the BRCA1 gene have a greatly increased lifetime incidence of breast and ovarian cancer, the molecular mechanisms responsible for this tissue-specific carcinogenesis remain undefined. The majority of these breast cancers are of t...

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Autors principals: Liu, Suling, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Foco, Hailey, Kleer, Celina G., Merajver, Sofia D., Dontu, Gabriela, Wicha, Max S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234204/
https://ncbi.nlm.nih.gov/pubmed/18230721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711613105
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