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Mammary stem cells, self-renewal pathways, and carcinogenesis

The mammary gland epithelial components are thought to arise from stem cells that undergo both self-renewal and differentiation. Self-renewal has been shown to be regulated by the Hedgehog, Notch, and Wnt pathways and the transcription factor B lymphoma Mo-MLV insertion region 1 (Bmi-1). We review d...

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Autors principals: Liu, Suling, Dontu, Gabriela, Wicha, Max S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143566/
https://ncbi.nlm.nih.gov/pubmed/15987436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1021
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