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Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells

The epithelial components of the mammary gland are thought to arise from stem cells with a capacity for self-renewal and multilineage differentiation. Furthermore, these cells and/or their immediate progeny may be targets for transformation. We have used both in vitro cultivation and a xenograft mou...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Liu, Suling, Dontu, Gabriela, Mantle, Ilia D., Patel, Shivani, Ahn, Nam-shik, Jackson, Kyle W., Suri, Prerna, Wicha, Max S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386278/
https://ncbi.nlm.nih.gov/pubmed/16778178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0054
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