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Survivin promotion of melanoma metastasis requires upregulation of α(5) integrin

Survivin is an apoptotic and mitotic regulator that is overexpressed in melanoma and a poor prognostic marker in patients with metastatic disease. We recently showed that Survivin enhances melanoma cell motility through Akt-dependent upregulation of α(5) integrin. However, the functional role of Sur...

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Detalles Bibliográficos
Main Authors: McKenzie, Jodi A., Liu, Tong, Jung, Jae Y., Jones, Benjamin B., Ekiz, Huseyin A., Welm, Alana L., Grossman, Douglas
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765044/
https://ncbi.nlm.nih.gov/pubmed/23640047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt155
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