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Survivin promotion of melanoma metastasis requires upregulation of α(5) integrin
Survivin is an apoptotic and mitotic regulator that is overexpressed in melanoma and a poor prognostic marker in patients with metastatic disease. We recently showed that Survivin enhances melanoma cell motility through Akt-dependent upregulation of α(5) integrin. However, the functional role of Sur...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765044/ https://ncbi.nlm.nih.gov/pubmed/23640047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt155 |
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