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Melanocyte expression of Survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice

We previously found the apoptosis inhibitor Survivin to be expressed in melanocytic nevi and melanoma, but not in normal melanocytes. To investigate the role of Survivin in melanoma development and progression, we examined the consequences of forced Survivin expression in melanocytes in vivo. Transg...

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Detalhes bibliográficos
Main Authors: Thomas, Joshua, Liu, Tong, Cotter, Murray A., Florell, Scott R., Robinette, Kyle, Hanks, Adrianne N., Grossman, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292453/
https://ncbi.nlm.nih.gov/pubmed/17545596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3669
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