N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of UV-induced melanoma in mice

UV radiation is the major environmental risk factor for melanoma and a potent inducer of oxidative stress, which is implicated in the pathogenesis of several malignancies. We evaluated whether the thiol antioxidant N-acetylcysteine (NAC) could protect melanocytes from UV-induced oxidative stress/dam...

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Détails bibliographiques
Auteurs principaux: Cotter, Murray A., Thomas, Joshua, Cassidy, Pamela, Robinette, Kyle, Jenkins, Noah, Scott, R. Florell, Leachman, Sancy, Samlowski, Wolfram E., Grossman, Douglas
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409148/
https://ncbi.nlm.nih.gov/pubmed/17908992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1187
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