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A phase II randomized placebo-controlled trial of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress in vivo

Oxidative stress plays a role in UV-induced melanoma, which may arise from melanocytic nevi. We investigated whether oral administration of the antioxidant N-acetylcysteine (NAC) could protect nevi from oxidative stress in vivo in the setting of acute UV exposure. The minimal erythemal dose (MED) wa...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Cassidy, Pamela B., Liu, Tong, Florell, Scott R., Honeggar, Matthew, Leachman, Sancy A., Boucher, Kenneth M., Grossman, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219848/
https://ncbi.nlm.nih.gov/pubmed/27920018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0162
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