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Use of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention

PURPOSE: Induction of oxidative stress has been implicated in UV-induced melanoma. We sought to determine whether the antioxidant N-acetylcysteine (NAC) could be safely administered to protect melanocytic nevi from the oxidative stress resulting from acute UV exposure. EXPERIMENTAL DESIGN: Patients...

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Detalhes bibliográficos
Main Authors: Goodson, Agnessa Gadeliya, Cotter, Murray A., Cassidy, Pamela, Wade, Mark, Florell, Scott R., Liu, Tong, Boucher, Kenneth M., Grossman, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787788/
https://ncbi.nlm.nih.gov/pubmed/19920101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1890
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