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Integrin αvβ3 and fibronectin upregulate Slug in cancer cells to promote clot invasion and metastasis
The blood clotting cascade is selectively involved in lung metastasis, but the reason for this selectivity is unclear. Here we show that tumor cells that metastasize predominantly to the lung, such as renal cell carcinoma (RCC) and soft tissue sarcoma (STS), have an inherent capacity to generate ext...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837455/ https://ncbi.nlm.nih.gov/pubmed/23966293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0602 |
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