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Relocation of CLIC1 Promotes Tumor Cell Invasion and Colonization of Fibrin

Chloride intracellular channel 1 (CLIC1) has been shown to be up-regulated in various malignancies but its exact function remains unclear. Here, it is revealed that CLIC1 is critical for the stability of invadopodia in endothelial and tumor cells embedded in a 3-dimensional (3D) matrix of fibrin. In...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Gurski, Lisa A., Knowles, Lynn M., Basse, Per H., Maranchie, Jodi K., Watkins, Simon C., Pilch, Jan
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336816/
https://ncbi.nlm.nih.gov/pubmed/25205595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0249
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