Stochastic Loss of Silencing of the Imprinted Ndn/NDN Allele, in a Mouse Model and Humans with Prader-Willi Syndrome, Has Functional Consequences

Genomic imprinting is a process that causes genes to be expressed from one allele only according to parental origin, the other allele being silent. Diseases can arise when the normally active alleles are not expressed. In this context, low level of expression of the normally silent alleles has been...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rieusset, Anne, Schaller, Fabienne, Unmehopa, Unga, Matarazzo, Valery, Watrin, Françoise, Linke, Matthias, Georges, Beatrice, Bischof, Jocelyn, Dijkstra, Femke, Bloemsma, Monique, Corby, Severine, Michel, François J., Wevrick, Rachel, Zechner, Ulrich, Swaab, Dick, Dudley, Keith, Bezin, Laurent, Muscatelli, Françoise
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764186/
https://ncbi.nlm.nih.gov/pubmed/24039599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003752
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg