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Natural breaking of the maternal silence at the mouse and human imprinted Prader-Willi locus: A whisper with functional consequences

Genomic imprinting is a normal process of epigenetic regulation leading some autosomal genes to be expressed from one parental allele only, the other parental allele being silenced. The reasons why this mechanism has been selected throughout evolution are not clear; however, expression dosage is cri...

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Bibliografiske detaljer
Main Authors: Matarazzo, Valery, Muscatelli, Françoise
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978896/
https://ncbi.nlm.nih.gov/pubmed/25003016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.27228
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