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The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

G protein-coupled receptors (GPCRs) exhibit a wide variety of signaling behaviors in response to different ligands. Using a small label on the cytosolic interface of TM6 (Cys-265), (19)F NMR spectra of the β(2) adrenoreceptor, β(2)AR, reconstituted in maltose–neopentyl glycol detergent micelles, rev...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Tae Hun, Chung, Ka Young, Manglik, Aashish, Hansen, Alexandar L., Dror, Ron O., Mildorf, Thomas J., Shaw, David E., Kobilka, Brian K., Prosser, R. Scott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763947/
https://ncbi.nlm.nih.gov/pubmed/23721409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja404305k
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