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The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor
G protein-coupled receptors (GPCRs) exhibit a wide variety of signaling behaviors in response to different ligands. Using a small label on the cytosolic interface of TM6 (Cys-265), (19)F NMR spectra of the β(2) adrenoreceptor, β(2)AR, reconstituted in maltose–neopentyl glycol detergent micelles, rev...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763947/ https://ncbi.nlm.nih.gov/pubmed/23721409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja404305k |
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