Adenosine Dioxolane Nucleoside Phosphoramidates As Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

[Image: see text] There are currently six nucleoside reverse transcriptase inhibitors (NRTI) that are FDA approved for human clinical use and these remain the backbone of current HIV therapy. In order for these NRTIs to be effective they need to be phosphorylated consecutively by cellular kinases to...

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Detalhes bibliográficos
Main Authors: Bondada, Lavanya, Detorio, Mervi, Bassit, Leda, Tao, Sijia, Montero, Catherine M., Singletary, Tyana M., Zhang, Hongwang, Zhou, Longhu, Cho, Jong-Hyun, Coats, Steven J., Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763849/
https://ncbi.nlm.nih.gov/pubmed/24015326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4001497
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