Adenosine Dioxolane Nucleoside Phosphoramidates As Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

[Image: see text] There are currently six nucleoside reverse transcriptase inhibitors (NRTI) that are FDA approved for human clinical use and these remain the backbone of current HIV therapy. In order for these NRTIs to be effective they need to be phosphorylated consecutively by cellular kinases to...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bondada, Lavanya, Detorio, Mervi, Bassit, Leda, Tao, Sijia, Montero, Catherine M., Singletary, Tyana M., Zhang, Hongwang, Zhou, Longhu, Cho, Jong-Hyun, Coats, Steven J., Schinazi, Raymond F.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2013
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763849/
https://ncbi.nlm.nih.gov/pubmed/24015326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4001497
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires