Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis

Aurora B kinase is an integral regulator of cytokinesis, as it stabilizes the intercellular canal within the midbody to ensure proper chromosomal segregation during cell division. Here we identified that the ubiquitin E3 ligase complex SCF(FBXL2) mediates Aurora B ubiquitination and degradation with...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chen, B B, Glasser, J R, Coon, T A, Mallampalli, R K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763433/
https://ncbi.nlm.nih.gov/pubmed/23928698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.271
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki