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Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation
The mammalian sperm nucleus is characterized by unique properties that are important for fertilization. Sperm DNA retains only small numbers of histones in distinct positions and the majority of the genome is protamine associated, which allows for extreme condensation and protection of the genetic m...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762462/ https://ncbi.nlm.nih.gov/pubmed/23729169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-013-0416-y |
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