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Disruption of Poly(ADP-Ribose) Homeostasis Affects Spermiogenesis and Sperm Chromatin Integrity in Mice

The major function of sperm is the delivery of the paternal genome to the metaphase II oocyte, ensuring transmission of the genetic information to the next generation. For successful fertilization and healthy offspring, sperm DNA must be protected from exogenous insults. This is achieved by packagin...

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Detalhes bibliográficos
Main Authors: Meyer-Ficca, Mirella L., Lonchar, Julia, Credidio, Christine, Ihara, Motomasa, Li, Yun, Wang, Zhao-Qi, Meyer, Ralph G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110478/
https://ncbi.nlm.nih.gov/pubmed/19264700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075390
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