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Disruption of Poly(ADP-Ribose) Homeostasis Affects Spermiogenesis and Sperm Chromatin Integrity in Mice

The major function of sperm is the delivery of the paternal genome to the metaphase II oocyte, ensuring transmission of the genetic information to the next generation. For successful fertilization and healthy offspring, sperm DNA must be protected from exogenous insults. This is achieved by packagin...

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Autores principales: Meyer-Ficca, Mirella L., Lonchar, Julia, Credidio, Christine, Ihara, Motomasa, Li, Yun, Wang, Zhao-Qi, Meyer, Ralph G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110478/
https://ncbi.nlm.nih.gov/pubmed/19264700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075390
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