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Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity

Poly(ADP-ribose)glycohydrolase (PARG) is the major enzyme capable of rapidly hydrolyzing poly(ADP-ribose)(PAR) formed by the diverse members of the PARP enzyme family. This study presents an alternative splice mechanism by which two novel PARG protein isoforms of 60 kDa and 55 kDa are expressed from...

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Bibliografske podrobnosti
Main Authors: Meyer, Ralph G., Meyer-Ficca, Mirella L., Whatcott, Clifford J., Jacobson, Elaine L., Jacobson, Myron K.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040269/
https://ncbi.nlm.nih.gov/pubmed/17509564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.03.043
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