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Neutral and weakly nonneutral sequence variants may define individuality

Large-scale computational analyses of the growing wealth of genome-variation data consistently tell two distinct stories. The first is expected: coding variants reported in disease-related databases significantly alter the function of affected proteins. The second is surprising: the genomes of healt...

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Библиографические подробности
Главные авторы: Bromberg, Yana, Kahn, Peter C., Rost, Burkhard
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761624/
https://ncbi.nlm.nih.gov/pubmed/23940345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216613110
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