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Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy

Modulation of estrogen signaling is one of the most successful modalities for the treatment of estrogen receptor (ER)-positive breast cancer, yet de novo and acquired resistance are frequent. Recent data suggests that the induction of autophagy may play a considerable role in promoting tumor cell su...

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Detalhes bibliográficos
Main Authors: Thomas, Scott, Thurn, Kenneth T., Biçaku, Elona, Marchion, Douglas C., Münster, Pamela N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760725/
https://ncbi.nlm.nih.gov/pubmed/21298336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1364-y
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