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Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer
Histone deacetylases (HDACs) regulate the acetylation of a variety of histone and nonhistone proteins, controlling the transcription and regulation of genes involved in cell cycle control, proliferation, survival, DNA repair and differentiation. Unsurprisingly, HDAC expression is frequently altered...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127396/ https://ncbi.nlm.nih.gov/pubmed/21345145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.11.2 |
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