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Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

Histone deacetylases (HDACs) regulate the acetylation of a variety of histone and nonhistone proteins, controlling the transcription and regulation of genes involved in cell cycle control, proliferation, survival, DNA repair and differentiation. Unsurprisingly, HDAC expression is frequently altered...

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Detalhes bibliográficos
Main Authors: Thurn, K Ted, Thomas, Scott, Moore, Amy, Munster, Pamela N
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127396/
https://ncbi.nlm.nih.gov/pubmed/21345145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.11.2
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