Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression

INTRODUCTION: The emergence of hormone therapy resistance, despite continued expression of the estrogen receptor (ER), is a major challenge to curing breast cancer. Recent clinical studies suggest that epigenetic modulation by histone deacetylase (HDAC) inhibitors reverses hormone therapy resistance...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Breast Cancer Res
Main Authors: Raha, Paromita, Thomas, Scott, Thurn, K Ted, Park, Jeenah, Munster, Pamela N
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367983/
https://ncbi.nlm.nih.gov/pubmed/25848915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0533-z
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares