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Autophagy Induction by Histone Deacetylase Inhibitors Inhibits HIV Type 1
Histone deacetylase inhibitors (HDACi) are being evaluated in a “shock-and-kill” therapeutic approach to reverse human immunodeficiency virus type-1 (HIV) latency from CD4(+) T cells. Using this approach, HDACi have induced HIV RNA synthesis in latently infected cells from some patients. The hope is...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335239/ https://ncbi.nlm.nih.gov/pubmed/25540204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605428 |
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