Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies()

Cyclooxygenase 2 (COX)-2 is induced by bacterial and viral infections and has complex, poorly understood roles in anti-pathogen immunity. Here, we use a knock-in luciferase reporter model to image Cox2 expression across a range of tissues in mice following treatment with the either the prototypical...

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Detalhes bibliográficos
Main Authors: Kirkby, Nicholas S., Zaiss, Anne K., Wright, William R., Jiao, Jing, Chan, Melissa V., Warner, Timothy D., R. Herschman, Harvey, Mitchell, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759847/
https://ncbi.nlm.nih.gov/pubmed/23850620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.07.006
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