Identification and Characterization of the Regions Involved in the Nuclear Translocation of the Heterodimeric Leishmanial DNA Topoisomerase IB

Leishmania donovani, the causative organism for visceral leishmaniasis, contains a unique heterodimeric DNA-topoisomerase IB (LdTopIB). LdTopIB is a heterodimer made up of a large subunit and a small subunit that must interact with each other to build an active enzyme able to solve the topological t...

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Main Authors: Prada, Christopher F., Álvarez-Velilla, Raquel, Díaz-Gozález, Rosario, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759442/
https://ncbi.nlm.nih.gov/pubmed/24023887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073565
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