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Deletion Study of DNA Topoisomerase IB from Leishmania donovani: Searching for a Minimal Functional Heterodimer

The substantial differences between trypanosomal and leishmanial DNA topoisomerase IB concerning to their homologues in mammals have provided a new lead in the study of the structural determinants that can be effectively targeted. Leishmania donovani, the causative agent of visceral leishmaniasis, c...

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Detalhes bibliográficos
Main Authors: Díaz González, Rosario, Pérez Pertejo, Yolanda, Ordóñez, David, Balaña-Fouce, Rafael, Reguera, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063514/
https://ncbi.nlm.nih.gov/pubmed/18000548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001177
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