Cargando...

Synthesis of Marine α-Methoxylated Fatty Acid Analogs that Effectively Inhibit the Topoisomerase IB from Leishmania donovani with a Mechanism Different from that of Camptothecin

Sponges biosynthesize α-methoxylated fatty acids with unusual biophysical and biological properties and in some cases they display enhanced anticancer activities. However, the antiprotozoal properties of the α-methoxylated fatty acids have been less studied. In this work, we describe the total synth...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Carballeira, Néstor M., Montano, Nashbly, Alvarez-Velilla, Raquel, Prada, Christopher F., Reguera, Rosa M., Balaña-Fouce, Rafael
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826128/
https://ncbi.nlm.nih.gov/pubmed/24084785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md11103661
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!