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Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models
Tuberous sclerosis complex (TSC) is a dominantly inherited disease with high penetrance and morbidity, and is caused by mutations in either of two genes, TSC1 or TSC2. Most affected individuals display severe neurological manifestations – such as intractable epilepsy, mental retardation and autism –...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Company of Biologists Limited
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759338/ https://ncbi.nlm.nih.gov/pubmed/23744272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012096 |
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