Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is characterized by developmental malformations of the cerebral cortex known as tubers, comprised of cells that exhibit enhanced mammalian target of rapamycin (mTOR) signaling. To date, there are no reports of mTORC1 and mTORC2 activation in fetal tubers or in neural...

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Autores principales: Tsai, Victoria, Parker, Whitney E., Orlova, Ksenia A., Baybis, Marianna, Chi, Anthony W.S., Berg, Benjamin D., Birnbaum, Jacqueline F., Estevez, Jacqueline, Okochi, Kei, Sarnat, Harvey B., Flores-Sarnat, Laura, Aronica, Eleonora, Crino, Peter B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888364/
https://ncbi.nlm.nih.gov/pubmed/23081885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs310
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