Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is characterized by developmental malformations of the cerebral cortex known as tubers, comprised of cells that exhibit enhanced mammalian target of rapamycin (mTOR) signaling. To date, there are no reports of mTORC1 and mTORC2 activation in fetal tubers or in neural...

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Main Authors: Tsai, Victoria, Parker, Whitney E., Orlova, Ksenia A., Baybis, Marianna, Chi, Anthony W.S., Berg, Benjamin D., Birnbaum, Jacqueline F., Estevez, Jacqueline, Okochi, Kei, Sarnat, Harvey B., Flores-Sarnat, Laura, Aronica, Eleonora, Crino, Peter B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888364/
https://ncbi.nlm.nih.gov/pubmed/23081885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs310
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