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Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is characterized by developmental malformations of the cerebral cortex known as tubers, comprised of cells that exhibit enhanced mammalian target of rapamycin (mTOR) signaling. To date, there are no reports of mTORC1 and mTORC2 activation in fetal tubers or in neural...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888364/ https://ncbi.nlm.nih.gov/pubmed/23081885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs310 |
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