Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis

Tuberous sclerosis complex (TSC) represents the prototypic monogenic disorder of the mammalian target of rapamycin (mTOR) pathway dysregulation. It provides the rational mechanistic basis of a direct link between gene mutation and brain pathology (structural and functional abnormalities) associated...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Zimmer, Till S., Broekaart, Diede W. M., Gruber, Victoria-Elisabeth, van Vliet, Erwin A., Mühlebner, Angelika, Aronica, Eleonora
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527496/
https://ncbi.nlm.nih.gov/pubmed/33041976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.01028
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