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Regulators and effectors of Siah ubiquitin ligases
The Siah ubiquitin ligases are members of the RING finger E3 ligases. The Siah E3s are conserved from fly to mammals. Primarily implicated in cellular stress responses, Siah ligases play a key role in hypoxia, through the regulation of HIF-1α transcription stability and activity. Concomitantly, phys...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758783/ https://ncbi.nlm.nih.gov/pubmed/23700162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-013-9636-2 |
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