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Dysregulation of ubiquitin ligases in cancer

Ubiquitin ligases are critical components of the ubiquitin proteasome system (UPS), which governs fundamental processes regulating normal cellular homeostasis, metabolism, and cell cycle in response to external stress signals and DNA damage. Among multiple steps of the UPS system required to regulat...

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Detalles Bibliográficos
Publicado en:Drug Resist Updat
Main Authors: Qi, Jianfei, Ronai, Ze’ev A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688568/
https://ncbi.nlm.nih.gov/pubmed/26690337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2015.09.001
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