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Ubiquitin ligases in oncogenic transformation and cancer therapy
The cellular response to external stress signals and DNA damage depends on the activity of ubiquitin ligases (E3s), which regulate numerous cellular processes, including homeostasis, metabolism and cell cycle progression. E3s recognize, interact with and ubiquitylate protein substrates in a temporal...
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| Vydáno v: | Nat Rev Cancer |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054770/ https://ncbi.nlm.nih.gov/pubmed/29242641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.105 |
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